Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Cdh1  cadherin 1   (Synonyms: Ecad, E-cad, E-cadherin, L-CAM, UM, uvomorulin)
Results	Reference
1*	J:69761 Angres B, Kim L, Jung R, Gessner R, Tauber R, LI-cadherin gene expression during mouse intestinal development. Dev Dyn. 2001 Jun;221(2):182-93
1	J:215166 Ayala de la Pena F, Kanasaki K, Kanasaki M, Vong S, Rovira C, Kalluri R, Specific activation of K-RasG12D allele in the bladder urothelium results in lung alveolar and vascular defects. PLoS One. 2014;9(4):e95888
1	J:105284 Birger Y, Davis J, Furusawa T, Rand E, Piatigorsky J, Bustin M, A role for chromosomal protein HMGN1 in corneal maturation. Differentiation. 2006 Feb;74(1):19-29
1*	J:33980 Butz S, Larue L, Expression of catenins during mouse embryonic development and in adult tissues. Cell Adhes Commun. 1995 Nov;3(4):337-52
1	J:301458 Chen G, Yang Y, Liu W, Huang L, Yang L, Lei Y, Wu H, Lei Z, Guo J, EpCAM is essential for maintenance of the small intestinal epithelium architecture via regulation of the expression and localization of proteins that compose adherens junctions. Int J Mol Med. 2021 Feb;47(2):621-632
1	J:176054 Collado MS, Thiede BR, Baker W, Askew C, Igbani LM, Corwin JT, The postnatal accumulation of junctional E-cadherin is inversely correlated with the capacity for supporting cells to convert directly into sensory hair cells in mammalian balance organs. J Neurosci. 2011 Aug 17;31(33):11855-66
1	J:178944 Daikoku T, Cha J, Sun X, Tranguch S, Xie H, Fujita T, Hirota Y, Lydon J, Demayo F, Maxson R, Dey SK, Conditional Deletion of MSX Homeobox Genes in the Uterus Inhibits Blastocyst Implantation by Altering Uterine Receptivity. Dev Cell. 2011 Dec 13;21(6):1014-25
1*	J:228856 DiTommaso T, Cottle DL, Pearson HB, Schluter H, Kaur P, Humbert PO, Smyth IM, Keratin 76 is required for tight junction function and maintenance of the skin barrier. PLoS Genet. 2014 Oct;10(10):e1004706
1	J:181140 Frezzetti D, Reale C, Cali G, Nitsch L, Fagman H, Nilsson O, Scarfo M, De Vita G, Di Lauro R, The microRNA-processing enzyme Dicer is essential for thyroid function. PLoS One. 2011;6(11):e27648
1	J:202907 Grigoryan T, Stein S, Qi J, Wende H, Garratt AN, Nave KA, Birchmeier C, Birchmeier W, Wnt/Rspondin/beta-catenin signals control axonal sorting and lineage progression in Schwann cell development. Proc Natl Acad Sci U S A. 2013 Nov 5;110(45):18174-9
1	J:166890 Hofmann JJ, Zovein AC, Koh H, Radtke F, Weinmaster G, Iruela-Arispe ML, Jagged1 in the portal vein mesenchyme regulates intrahepatic bile duct development: insights into Alagille syndrome. Development. 2010 Dec;137(23):4061-72
1	J:83398 Hollnagel A, Grund C, Franke WW, Arnold HH, The cell adhesion molecule M-cadherin is not essential for muscle development and regeneration. Mol Cell Biol. 2002 Jul;22(13):4760-70
1	J:280081 Hou G, Wu V, Singh G, Holzman LB, Tsui CC, Ret is critical for podocyte survival following glomerular injury in vivo. Am J Physiol Renal Physiol. 2015 Apr 1;308(7):F774-83
1*	J:97304 Ihrie RA, Marques MR, Nguyen BT, Horner JS, Papazoglu C, Bronson RT, Mills AA, Attardi LD, Perp is a p63-regulated gene essential for epithelial integrity. Cell. 2005 Mar 25;120(6):843-56
1	J:303495 Iwaki A, Moriwaki K, Sobajima T, Taniguchi M, Yoshimura SI, Kunii M, Kanda S, Kamada Y, Miyoshi E, Harada A, Loss of Rab6a in the small intestine causes lipid accumulation and epithelial cell death from lactation. FASEB J. 2020 Jul;34(7):9450-9465
1	J:97750 Jamora C, Lee P, Kocieniewski P, Azhar M, Hosokawa R, Chai Y, Fuchs E, A signaling pathway involving TGF-beta2 and snail in hair follicle morphogenesis. PLoS Biol. 2005 Jan;3(1):e11
1	J:115286 Jha RK, Titus S, Saxena D, Kumar PG, Laloraya M, Profiling of E-cadherin, beta-catenin and Ca(2+) in embryo-uterine interactions at implantation. FEBS Lett. 2006 Oct 16;580(24):5653-60
1	J:255472 Jimenez-Caliani AJ, Pillich R, Yang W, Diaferia GR, Meda P, Crisa L, Cirulli V, alphaE-Catenin Is a Positive Regulator of Pancreatic Islet Cell Lineage Differentiation. Cell Rep. 2017 Aug 8;20(6):1295-1306
1	J:220308 Jin Y, Shenoy AK, Doernberg S, Chen H, Luo H, Shen H, Lin T, Tarrash M, Cai Q, Hu X, Fiske R, Chen T, Wu L, Mohammed KA, Rottiers V, Lee SS, Lu J, FBXO11 promotes ubiquitination of the Snail family of transcription factors in cancer progression and epidermal development. Cancer Lett. 2015 Jun 28;362(1):70-82
1*	J:54660 Kamiya A, Kinoshita T, Ito Y, Matsui T, Morikawa Y, Senba E, Nakashima K, Taga T, Yoshida K, Kishimoto T, Miyajima A, Fetal liver development requires a paracrine action of oncostatin M through the gp130 signal transducer. EMBO J. 1999 Apr 15;18(8):2127-36
1*	J:316578 Lade A, Ranganathan S, Luo J, Monga SP, Calpain induces N-terminal truncation of beta-catenin in normal murine liver development: diagnostic implications in hepatoblastomas. J Biol Chem. 2012 Jun 29;287(27):22789-98
1	J:306330 Le D, Lim S, Min KW, Park JW, Kim Y, Ha T, Moon KH, Wagner KU, Kim JW, Tsg101 Is Necessary for the Establishment and Maintenance of Mouse Retinal Pigment Epithelial Cell Polarity. Mol Cells. 2021 Mar 31;44(3):168-178
1	J:161852 Libusova L, Stemmler MP, Hierholzer A, Schwarz H, Kemler R, N-cadherin can structurally substitute for E-cadherin during intestinal development but leads to polyp formation. Development. 2010 Jul;137(14):2297-305
1	J:164479 Lozovatsky L, Abayasekara N, Piawah S, Walther Z, CASK deletion in intestinal epithelia causes mislocalization of LIN7C and the DLG1/Scrib polarity complex without affecting cell polarity. Mol Biol Cell. 2009 Nov;20(21):4489-99
1*	J:78246 Menko AS, Zhang L, Schiano F, Kreidberg JA, Kukuruzinska MA, Regulation of cadherin junctions during mouse submandibular gland development. Dev Dyn. 2002 Jul;224(3):321-33
1	J:92091 Micsenyi A, Tan X, Sneddon T, Luo JH, Michalopoulos GK, Monga SP, Beta-catenin is temporally regulated during normal liver development. Gastroenterology. 2004 Apr;126(4):1134-46
1	J:282576 Nakajima K, Ono M, Radovic U, Dizdarevic S, Tomizawa SI, Kuroha K, Nagamatsu G, Hoshi I, Matsunaga R, Shirakawa T, Kurosawa T, Miyazaki Y, Seki M, Suzuki Y, Koseki H, Nakamura M, Suda T, Ohbo K, Lack of whey acidic protein (WAP) four-disulfide core domain protease inhibitor 2 (WFDC2) causes neonatal death from respiratory failure in mice. Dis Model Mech. 2019 Nov 12;12(11):dmm040139
1	J:124940 Nechiporuk T, Fernandez TE, Vasioukhin V, Failure of epithelial tube maintenance causes hydrocephalus and renal cysts in dlg5(-/-) mice. Dev Cell. 2007 Sep;13(3):338-50
1*	J:235530 Niu W, Wang Y, Wang Z, Xin Q, Wang Y, Feng L, Zhao L, Wen J, Zhang H, Wang C, Xia G, JNK signaling regulates E-cadherin junctions in germline cysts and determines primordial follicle formation in mice. Development. 2016 May 15;143(10):1778-87
1*	J:31272 Peyrieras N, Hyafil F, Louvard D, Ploegh HL, Jacob F, Uvomorulin: a nonintegral membrane protein of early mouse embryo. Proc Natl Acad Sci U S A. 1983 Oct;80(20):6274-7
1	J:72798 Pin CL, Rukstalis JM, Johnson C, Konieczny SF, The bHLH transcription factor Mist1 is required to maintain exocrine pancreas cell organization and acinar cell identity. J Cell Biol. 2001 Nov 12;155(4):519-30
1	J:131815 Pontoriero GF, Deschamps P, Ashery-Padan R, Wong R, Yang Y, Zavadil J, Cvekl A, Sullivan S, Williams T, West-Mays JA, Cell autonomous roles for AP-2alpha in lens vesicle separation and maintenance of the lens epithelial cell phenotype. Dev Dyn. 2008 Mar;237(3):602-17
1	J:242076 Poobalasingam T, Yates LL, Walker SA, Pereira M, Gross NY, Ali A, Kolatsi-Joannou M, Jarvelin MR, Pekkanen J, Papakrivopoulou E, Long DA, Griffiths M, Wagner D, Konigshoff M, Hind M, Minelli C, Lloyd CM, Dean CH, Heterozygous Vangl2Looptail mice reveal novel roles for the planar cell polarity pathway in adult lung homeostasis and repair. Dis Model Mech. 2017 Apr 01;10(4):409-423
1	J:311917 Qiu X, Wei R, Li Y, Zhu Q, Xiong C, Chen Y, Zhang Y, Lu K, He F, Zhang L, NEDL2 regulates enteric nervous system and kidney development in its Nedd8 ligase activity-dependent manner. Oncotarget. 2016 May 24;7(21):31440-53
1	J:151538 Rivera C, Yamben IF, Shatadal S, Waldof M, Robinson ML, Griep AE, Cell-autonomous requirements for Dlg-1 for lens epithelial cell structure and fiber cell morphogenesis. Dev Dyn. 2009 Jul 21;238(9):2292-2308
1	J:269511 Roy A, Skibo J, Kalume F, Ni J, Rankin S, Lu Y, Dobyns WB, Mills GB, Zhao JJ, Baker SJ, Millen KJ, Mouse models of human PIK3CA-related brain overgrowth have acutely treatable epilepsy. Elife. 2015 Dec 3;4:e12703
1*	J:1309 Sefton M, Johnson MH, Clayton L, Synthesis and phosphorylation of uvomorulin during mouse early development. Development. 1992 May;115(1):313-8
1	J:174303 Sekiya S, Suzuki A, Glycogen synthase kinase 3{beta}-dependent Snail degradation directs hepatocyte proliferation in normal liver regeneration. Proc Natl Acad Sci U S A. 2011 Jul 5;108(27):11175-80
1	J:31207 Shimamura K, Takahashi T, Takeichi M, E-cadherin expression in a particular subset of sensory neurons. Dev Biol. 1992 Aug;152(2):242-54
1*	J:29896 Sjodin A, Dahl U, Semb H, Mouse R-cadherin: expression during the organogenesis of pancreas and gastrointestinal tract. Exp Cell Res. 1995 Dec;221(2):413-25
1	J:186876 Sugiyama N, Tsukiyama T, Yamaguchi TP, Yokoyama T, The canonical Wnt signaling pathway is not involved in renal cyst development in the kidneys of inv mutant mice. Kidney Int. 2011 May;79(9):957-65
1	J:261068 Szabo R, Bugge TH, Loss of HAI-2 in mice with decreased prostasin activity leads to an early-onset intestinal failure resembling congenital tufting enteropathy. PLoS One. 2018;13(4):e0194660
1	J:144091 Tinkle CL, Pasolli HA, Stokes N, Fuchs E, New insights into cadherin function in epidermal sheet formation and maintenance of tissue integrity. Proc Natl Acad Sci U S A. 2008 Oct 7;105(40):15405-10
1	J:258557 Tu Z, Wang Q, Cui T, Wang J, Ran H, Bao H, Lu J, Wang B, Lydon JP, DeMayo F, Zhang S, Kong S, Wu X, Wang H, Uterine RAC1 via Pak1-ERM signaling directs normal luminal epithelial integrity conducive to on-time embryo implantation in mice. Cell Death Differ. 2016 Jan;23(1):169-81
1	J:97223 Tunggal JA, Helfrich I, Schmitz A, Schwarz H, Gunzel D, Fromm M, Kemler R, Krieg T, Niessen CM, E-cadherin is essential for in vivo epidermal barrier function by regulating tight junctions. EMBO J. 2005 Mar 23;24(6):1146-56
1	J:73084 Vasioukhin V, Bowers E, Bauer C, Degenstein L, Fuchs E, Desmoplakin is essential in epidermal sheet formation. Nat Cell Biol. 2001 Dec;3(12):1076-85
1	J:31274 Vestweber D, Gossler A, Boller K, Kemler R, Expression and distribution of cell adhesion molecule uvomorulin in mouse preimplantation embryos. Dev Biol. 1987 Dec;124(2):451-6
1*	J:31273 Vestweber D, Ocklind C, Gossler A, Odin P, Obrink B, Kemler R, Comparison of two cell-adhesion molecules, uvomorulin and cell-CAM 105. Exp Cell Res. 1985 Apr;157(2):451-61
1	J:105811 Wu X, Quondamatteo F, Lefever T, Czuchra A, Meyer H, Chrostek A, Paus R, Langbein L, Brakebusch C, Cdc42 controls progenitor cell differentiation and beta-catenin turnover in skin. Genes Dev. 2006 Mar 1;20(5):571-85
1	J:297219 Xu J, Tang Y, Sheng X, Tian Y, Deng M, Du S, Lv C, Li G, Pan Y, Song Y, Lou P, Luo Y, Li Y, Zhang B, Chen Y, Liu Z, Cong Y, Plikus MV, Meng Q, Zhou Z, Yu Z, Secreted stromal protein ISLR promotes intestinal regeneration by suppressing epithelial Hippo signaling. EMBO J. 2020 Apr 1;39(7):e103255
1	J:204591 Yamben IF, Rachel RA, Shatadal S, Copeland NG, Jenkins NA, Warming S, Griep AE, Scrib is required for epithelial cell identity and prevents epithelial to mesenchymal transition in the mouse. Dev Biol. 2013 Dec 1;384(1):41-52
1	J:344311 Yan W, Chen S, Wang Y, You Y, Lu Y, Wang W, Wu B, Du J, Peng S, Cai W, Xiao Y, Loss of Mptx2 alters bacteria composition and intestinal homeostasis potentially by impairing autophagy. Commun Biol. 2024 Jan 13;7(1):94
1	J:142321 Zahn C, Jaschke A, Weiske J, Hommel A, Hesse D, Augustin R, Lu L, Hong W, Florian S, Scheepers A, Joost HG, Huber O, Schurmann A, ADP-ribosylation factor-like GTPase ARFRP1 is required for trans-Golgi to plasma membrane trafficking of E-cadherin. J Biol Chem. 2008 Oct 3;283(40):27179-88
1	J:182350 Zanucco E, Gotz R, Potapenko T, Carraretto I, Ceteci S, Ceteci F, Seeger W, Savai R, Rapp UR, Expression of B-RAF V600E in type II pneumocytes causes abnormalities in alveolar formation, airspace enlargement and tumor formation in mice. PLoS One. 2011;6(12):e29093
1	J:343081 Zhang R, Pan S, Zheng S, Liao Q, Jiang Z, Wang D, Li X, Hu A, Li X, Zhu Y, Shen X, Lei J, Zhong S, Zhang X, Huang L, Wang X, Huang L, Shen L, Song BL, Zhao JW, Wang Z, Yang B, Guo X, Lipid-anchored proteasomes control membrane protein homeostasis. Sci Adv. 2023 Dec;9(48):eadj4605